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Last summer we had a builder doing some work, nice chap, very chatty. I couldn’t help but notice the food he brought in and by the end of the chat we had established his blood sugars were up and down like a yo-yo, and he was putting on weight as a result.

I sent him the article below and suggested ACV with meals, fewer carbs, more protein/fat and eat the protein first, carbs last, and 16-8 fasting, easy.


He also mentioned his wife had gone vegan the year before and had now developed severe migraines.

So bad he had paid to go privately to see a neurologist.

Sadly, they know remarkably little about the actual causes, but a lot about drug options.

Thus, she started on the conveyor belt of medication.

He was back yesterday and his wife is now having “migraine” most days and is often bed-bound and saying this like “what’s the point of carrying on”.

She is now pinning her hopes on the miracle drug for migraine, a calcitonin gene related peptide (CGRP) inhibitor.

CGRP is the last trigger in a complex chemical sequence, that is underpinned by mitochondrial dysfunction and neuro-inflammation.

CGRP is the tipping point for metabolic collapse in the cell. 

Do these drugs work?

Yes they do:

But, they are not a cure and the price you pay for drugs that are potent years down the line. 

But the thing is, we know CGRP is produced after provocation from neuro-inflammation and nociception. 

CGRP is not a bad faith actor, a “bad molecule” out to get you. 

It is a symptomatic, downstream, functional expression of dysfunctional mitochondria, neuro-inflammation (both cause each other) and nociception. 

Sure we can flatten it to a degree with the new miracle drug, and pay the price in side effects later. 

But how about we look for the root cause of inflammation, mitochondrial dysfunction and nociception – could that work as well as the new drug? 

Check this out, vitamin D for migraine (remember low vitamin D = higher inflammation) and they are looking at migraines levels AND CGRP. 

Vitamin D at 2000 IU daily (a modest dose) gave them 36% less h/a per month and a 34% reduction related disability (by not means a cure but a clinically significant reduction). 

And that is just one part of a complex jigsaw that is migraines. 

We also use carnitine (only found in meat or Meta-Boost):





And B12 (only found in meat)


Ultimately, that is why we have a protocol all about migraine which includes the neuro-mechanical components as well as bio-chemical.

I strongly suspect his wife has slowly depleted her nutrients by eating a low nutrient dense diet (ultra-processed vegan) and triggered a fragile central nervous system into metabolic collapse, possibly with a little help from her upper cervicals and TMJ/teeth.

If you want to know when to use Meta-Boost, check out this 1 minute video on when to use it